Sens-is awareness test

The Sens-is sensitization test, initially developed by Immunosearch, is based on the use of a reconstructed skin model (Episkin®) and the evaluation by RT-PCR of the expression of 62 genes selected as being relevant in the biological sensitization process.
While most tests currently available for the assessment of sensitization only give a qualitative response, Sens-is is the only test giving a quantitative response that correlates with the mouse model of LLNA (OECD TG 429) .
Advantages of the Sens-is test
  • Quantitative assessment in correlation with the LLNA
  • Episkin ® reconstituted epidermis
  • Currently being validated by the OECD
Sens-is compared to other tests